亚州视频一区二区三区,美乳人妻三级,亚洲色丝袜脚交,潮喷水Xxxxxx

最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
首頁>>免疫學(xué)>>一抗>>FasL抗體
FasL抗體
  • 產(chǎn)品貨號(hào):
    BN41512R
  • 中文名稱:
    FasL抗體
  • 英文名稱:
    Rabbit anti-Fas Ligand Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號(hào)

    產(chǎn)品規(guī)格

    售價(jià)

    備注

  • BN41512R-50ul

    50ul

    ¥1486.00

    交叉反應(yīng):Rat,Mouse,Human(predicted:Cow) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41512R-100ul

    100ul

    ¥2360.00

    交叉反應(yīng):Rat,Mouse,Human(predicted:Cow) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41512R-200ul

    200ul

    ¥3490.00

    交叉反應(yīng):Rat,Mouse,Human(predicted:Cow) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Fas Ligand
中文名稱FasL抗體
別    名APO1L; Apoptosis (APO 1) antigen ligand 1; Fas-L; Apoptosis antigen ligand 1; APTL; CD178; CD-178; CD 178; CD95L; CD95 ligand; CD95-L; CD95L protein; FAS antigen ligand; Fas L; Fas Ligand; FASL; Fasl; Fas ligand (TNF superfamily member 6); Generalized lymphoproliferative disease; TNF superfamily member 6; TNFSF6; Tumor necrosis factor ligand superfamily member 6; TNFL6_HUMAN; Apoptosis antigen ligand; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; FASLG.  




研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞凋亡  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Cow, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量31kDa
細(xì)胞定位細(xì)胞核 細(xì)胞膜 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Fas Ligand:196-281/281 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹FasL (CD95L) is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. Homotrimer (Probable). May be released as type II membrane protein. Belongs to the tumor necrosis factor family

Function:
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Subunit:
Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FGR, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1.

Subcellular Location:
Cell membrane; Single-pass type II membrane protein. Secreted. Cytoplasmic vesicle lumen. Lysosome lumen. Note=May be released into the extracellular fluid, probably by cleavage form the cell surface. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination.

Post-translational modifications:
N-glycosylated.
The soluble form derives from the membrane form by proteolytic processing.
Phosphorylated by FGR on tyrosine residues; this is required for ubiquitination and subsequent internalization.
Monoubiquitinated.

DISEASE:
Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.

Similarity:
Belongs to the tumor necrosis factor family.

SWISS:
P48023

Gene ID:
356

Database links:

Entrez Gene: 356 Human

Entrez Gene: 14103 Mouse

Entrez Gene: 25385 Rat

Omim: 134638 Human

SwissProt: P48023 Human

SwissProt: P41047 Mouse

SwissProt: P36940 Rat

Unigene: 2007 Human

Unigene: 3355 Mouse

Unigene: 9725 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Fas-L 是一個(gè)與TNFRSF6/FAS 結(jié)合的細(xì)胞因子,一個(gè)轉(zhuǎn)導(dǎo)凋亡信號(hào)到細(xì)胞內(nèi)的一個(gè)受體。他可能參與T-細(xì)胞調(diào)節(jié)凋亡細(xì)胞毒性和T-細(xì)胞的發(fā)育。調(diào)節(jié)凋亡的TNFRSF6/FAS 在外周組織耐受性方面和抗原刺激成熟淋巴細(xì)胞自殺中起作用。FasL誘導(dǎo)物受體TNFRSF6B/DcR3結(jié)合調(diào)節(jié)其作用。
FasL只表達(dá)于活化的淋巴細(xì)胞,但在小鼠睪丸中可見高表達(dá)的FasL;分子量為36-43kDa。屬于TNF家族。


日本免费视频试看| 午夜AV在线一二三| 欧美香蕉视| 艹逼视频在线播放| 加勒比成人综合网| 欧美日韩亚洲无码综合| 日韩欧美一区不卡人妻| 嗯啊啊我要了视频| 国内美女AV网站| 亚洲av分类在线| 精品久久视频观看| 91网福利67国产,亚洲| 久久v久悠| 国产人妻一区二区三区免费| 性生活免费视频久久久| 久久久久久久妹子精品| 天天久久艹| 欧美大黄美女内射视频| 成年人黄色片久久久久久久| 亚洲伦理专区| 精品探花一区二区三区| 日本亚洲欧美综合视频在线播放| 欧美日韩1级在线观看| 下欧美日韩在线不卡| 图片亚洲 欧美一区| 欧美性综合天天玩夜夜玩狠狠的玩| 日韩啪啪啪啪啪| 中文字幕精品麻豆| 殴欧美日韩不卡| 国产尤物精品视频一区二区三区| 国产网站啊啊h| 中文丝袜少妇被干| 精品国产乱码老| 日本少妇久久免费| 爽天天爽天天干| 夜夜嗨AV首页| 亚州熟妇XXXXX| 欧美不卡一级在线| 最新人妻资源在线| 国产日韩综合精品一区二| 美女白虎久久国产精品|