亚州视频一区二区三区,美乳人妻三级,亚洲色丝袜脚交,潮喷水Xxxxxx

最近搜索:細胞培養(yǎng) 微生物學 分子生物 生物化學
首頁>>免疫學>>一抗>>甲狀腺受體相互作用蛋白15抗體
甲狀腺受體相互作用蛋白15抗體
  • 產(chǎn)品貨號:
    BN41366R
  • 中文名稱:
    甲狀腺受體相互作用蛋白15抗體
  • 英文名稱:
    Rabbit anti-COPS2 Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41366R-100ul

    100ul

    ¥2360.00

    交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41366R-200ul

    200ul

    ¥3490.00

    交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱COPS2
中文名稱甲狀腺受體相互作用蛋白15抗體
別    名ALIEN; Alien homolog; COP 9; COP9; COP9 constitutive photomorphogenic homolog subunit 2; COP9 signalosome complex subunit 2; COPS 2; Cops2; CSN2; CSN2_HUMAN; JAB1 containing signalosome subunit 2; JAB1-containing signalosome subunit 2; SGN 2; SGN2; Signalosome subunit 2; Thyroid Hormone Receptor Interactor15; Thyroid Hormone Receptor Interactor 15; Thyroid receptor-interacting protein 15; TR-interacting protein 15; TRIP 15; TRIP-15.  
研究領域細胞生物  免疫學  染色質(zhì)和核信號  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
細胞定位細胞核 細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human COPS2/TRIP15:51-185/443 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Function:
Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Subunit:
Interacts with NIF3L1 (By similarity). Component of the CSN complex, composed of COPS1/GPS1, COPS2, COPS3, COPS4, COPS5, COP6, COPS7 (COPS7A or COPS7B) and COPS8. In the complex, it probably interacts directly with COPS1, COPS4, COPS5 COPS6 and COPS7 (COPS7A or COPS7B). Interacts with CUL1 and CUL2. Specifically interacts with the ligand binding domain of the thyroid receptor (TR). Does not require the presence of thyroid hormone for its interaction. Interacts with IRF8/ICSBP1 and with nuclear receptors NR2F1 and NR0B1.

Subcellular Location:
Cytoplasm. Nucleus.

Post-translational modifications:
Phosphorylated by CK2 and PKD kinases.

Similarity:
Belongs to the CSN2 family.
Contains 1 PCI domain.

SWISS:
P61201

Gene ID:
9318

Database links:

Entrez Gene: 9318 Human

Entrez Gene: 12848 Mouse

Entrez Gene: 261736 Rat

Omim: 604508 Human

SwissProt: P61201 Human

SwissProt: P61202 Mouse

SwissProt: P61203 Rat

Unigene: 369614 Human

Unigene: 3596 Mouse

Unigene: 11556 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


porn超碰一区二区| 日韩丝袜伦理电影一区二区三区| 草逼视频免费网站| 日韩精品麻豆| 国产日韩91久久| 性色AV吧一区| 区二区三区在线 | 欧洲| av亚洲男人天堂网站| 天天插天天干成人av| 超porn在线视频综合官网| 久久久无码精品亚洲日韩动图| 午夜福利青春视频| 操操夜夜操| 国产老熟女吞精| 操逼日常视频| 一区二区三区四区干| 福利一区福利二区福利刺激| 就爱成人综合网| 爆操人妻后入人妻| 久久精品亚洲婷婷| 性色生活在线播放网站| 麻豆精品区二区| 艹逼抽插内射| 少妇人妻一区二区三区久久| 欧美日韩国产伦| 黄色不卡视频| 在线+国产+欧美| 不要啊啊啊啊啊啊视频| 五月婷婷综合激情人妻| 亚洲欧成人福利在线| 国产精品美女黄网站| 亚欧超碰一区二区三区| 欧美日本一区二区视频在线| 女人被躁到高潮嗷嗷叫游戏| 国产欧美深浅插| 韩国三级在线播久_久久精品| 亚洲操| 天堂久久久久久久久久久| 我要AV网| 国产精品欧美综合| 色婷婷AV少妇精品无码|