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產(chǎn)品規(guī)格
售價
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BN41198R-100ul
100ul
￥2360.00
交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB
BN41198R-200ul
200ul
￥3490.00
交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB
產(chǎn)品描述
| 英文名稱 | ZNF379 |
| 中文名稱 | 鋅指蛋白379抗體 |
| 別 名 | CXorf11; DHHC9; Palmitoyltransferase ZDHHC9; ZDHHC 9; ZDHHC10; Zinc finger DHHC domain containing protein 9; Zinc finger protein 379; ZNF379; ZNF380; ZDHC9_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 信號轉(zhuǎn)導(dǎo) 腫瘤細胞生物標志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF379/ZDHHC9:118-155/364 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010]. Function: The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. Subunit: Interacts with GOLGA7. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Tissue Specificity: Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes. DISEASE: Defects in ZDHHC9 are the cause of mental retardation syndromic X-linked ZDHHC9-related (MRXSZ) [MIM:300799]. A disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Some patients have marfanoid habitus as an additional feature. Similarity: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. Contains 1 DHHC-type zinc finger. SWISS: Q9Y397 Gene ID: 51114 Database links: Entrez Gene: 51114 Human Entrez Gene: 208884 Mouse Omim: 300646 Human SwissProt: Q9Y397 Human SwissProt: P59268 Mouse Unigene: 193566 Human Unigene: 207367 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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