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產(chǎn)品規(guī)格
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BN40964R-100ul
100ul
￥2360.00
交叉反應(yīng)：Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN40964R-200ul
200ul
￥3490.00
交叉反應(yīng)：Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN40964R-50ul
50ul
￥1486.00
交叉反應(yīng)：Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
產(chǎn)品描述
| 英文名稱 | GM-CSF |
| 中文名稱 | 粒細(xì)胞-巨噬細(xì)胞克隆刺激因子抗體 |
| 別 名 | Granulocyte-Macrophage Colony Stimulating Factor; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; Colony stimulating factor; CSF 2; CSF Alpha; CSF; CSF2; Eosinophil Colony Stimulating Factor; GMCSF; Granulocyte Macrophage Colony Stimulating Factor; MGC131935; MGC138897; Molgramostin; Pluripoietin Alpha; Sargramostim; granulocyte-macrophage colony-stimulating factor precursor; CSF2_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 趨化因子 細(xì)胞表面分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Recombinant protein) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 14kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GM-CSF:65-144/144 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]. Function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Subunit: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits. Subcellular Location: Secreted. Similarity: Belongs to the GM-CSF family. SWISS: P04141 Gene ID: 1437 Database links: Entrez Gene: 1437 Human Omim: 138960 Human SwissProt: P04141 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GM-CSF是血管內(nèi)皮細(xì)胞、單核細(xì)胞和成纖維細(xì)胞合成的糖蛋白。能促進(jìn)中性粒細(xì)胞成熟；刺激成熟的粒細(xì)胞從骨髓釋出；增強(qiáng)中性粒細(xì)胞趨化及吞噬功能。 |
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